Archive for 28 diciembre 2009

GlaxoSmithKline – Origins



GlaxoSmithKline = Merger of GlaxoWellcome and SmithKline Beecham in 2000. $75,961 million, 2nd major M&A in the 2000s.
GlaxoWellcome = Merger of Burroughs Wellcome & Co. and Glaxo Laboratories in 1995.
SmithKline Beecham = Merger of Beecham and SmithKline in 1989.
– GlaxoSmithKline is a corporate member of the Council on Foreign Relations.


– 1878: Silas Mainville Burroughs travels to London as an agent for John Wyeth & Bro (Wyeth Pharmaceuticals) and founds Burroughs & Co., which imported American drugs into the U.K.
– 1880: Silas Mainville Burroughs’s friend Henry Wellcome joins the company and the name is changed into Burroughs Wellcome & Company.
– 1904: Glaxo is founded in Bunnythorpe, New Zealand, as a baby food manufacturer processing local milk into a baby food.
– 1935: Glaxo becomes Glaxo Laboratories and opens new units in London.
– 1947: Glaxo Laboratories buys Joseph Nathan.
– 1958: Glaxo Laboratories buys Allen & Hanburys.
– 1959: The Wellcome Company buys McDougall & Robertson Inc. to become more active in animal health.
– 1978: Glaxo Laboratories buys Meyer Laboratories Inc.
– 1987: The AIDS treatment Retrovir (zidovudine) is launched by Wellcome. Glaxo introduces the oral antibiotic Zinnat (cefuroxime axetil).
– 1991: Glaxo launches novel treatment for migraine, Imigran (sumatriptan), Lacipil (lacidipine) for high blood pressure, and Cutivate (fluticasone propionate) in the U.S. for skin diseases.
– 1992: Mepron (atovaquone) for AIDS-related pneumonia is introduced by Burroughs Wellcome in the U.S.
– 1993: Glaxo introduces Flixotide (fluticasone propionate) for bronchial conditions.
– 1995: Glaxo and Wellcome merge to form Glaxo Wellcome. Glaxo Wellcome acquires California-based Affymax, a leader in the field of combinatorial chemistry. The Queen opens Glaxo Wellcome‘s Medicines Research Centre at Stevenage in England. Valtrex (valaciclovir) is launched as an anti-herpes successor to Zovirax (acyclovir).
– 1998: GlaxoWellcome buys Polfa Poznan Company in Poland.

Henry Solomon Wellcome
– Freemason.
– 1924: Creates holding company, The Wellcome Foundation Limited.
– 1932: Knighted and made Honorary Fellow of the Royal College of Surgeons of England.
– Collection of around 1.5 million books and objects relating to history and medicine. As well as artefacts specific to medicine and healing, it included large quantities of weapons, bales of fabric, furniture, ancient cooking implements, porcelain, glassware, statues, coins, medals, objets d’art and even torture instruments. He also acquired a sample of the hair of various historical figures, including George Washington, George III, Napoleon Bonaparte and the Duke of Wellington.
– Between 1911 and 1914 funded excavations at Jebel Moya, south of Khartoum, Sudan, hiring 4000 people to excavate.
– Abiding interest in Native American culture. Through financial support and political lobbying helped establish a model Christian community amongst the Tsimshean people in British Columbia and establish an alternative site in Alaska.
– 1936: On his death the Wellcome Trust is established.

SmithKline Beecham

– 1830: John K. Smith and his brother-in-law John Gilbert open a drugstore in Philadelphia.
– 1841: John Gilbert withdraws and Smith is joined by his younger brother George to form John K Smith & Co.
– 1842: Thomas Beecham launches his Beecham’s Pills laxative in England giving birth to the Beecham Group.
– 1859: Beecham opens the world’s first factory to be built solely for making medicines at St Helens in England.
– 1865: Mahlon Kline joins John K Smith & Co.
– 1875: Mahlon K Smith & Co is renamed Smith, Kline and Co.
– 1891: Merges with French, Richard & Co.
– 1929: Smith, Kline & French Co is renamed Smith Kline & French Laboratories and becomes more focused on research.
– 1930’s: Smith Kline & French Laboratories buys Norden Laboratories, a business doing research into animal health.
– 1938: Beecham acquires Macleans Ltd and Eno’s Proprietaries Ltd.
– 1939: Beecham acquires County Perfumery Co Ltd, manufacturers of Brylcreem, a men’s hair application.
– 1943: Beecham Research Laboratories is formed with the mission to focus exclusively on basic pharmaceutical research.
– 1945: Beecham Group Ltd is established, replacing Beecham Pills Ltd and Beecham Estates Ltd, later known as Beecham Group plc, and incorporates Beecham Research Laboratories.
– 1949: Beecham Group Ltd acquires C L Bencard Ltd, a company specialising in allergy vaccines.
– 1963: Smith Kline & French Laboratories buys Recherche et Industrie Thérapeutiques (Belgium) to order to focus on vaccines.
– 1969: Smith Kline & French Laboratories buys 7 laboratories in Canada and the U.S.
– 1982: Smith Kline & French Laboratories buys Allergan, a manufacturer of eye and skincare products, and merges with Beckman Inc. changing its name to SmithKline Beckman.
– 1986: Beecham acquires the U.S. firm Norcliff Thayer.
– 1988: SmithKline BioScience Laboratories buys its biggest competitor, International Clinical Laboratories Inc.
– 1989: SmithKline Beckman and The Beecham Group plc merge to form SmithKline Beecham plc.
– 1991: Seroxat/Paxil (paroxetine hydrochloride) is launched in the U.K.
– 1992: Havrix hepatitis A vaccine, inactivated, the world’s first hepatitis A vaccine, is launched in 6 European markets.
– 1993: SmithKline Beecham and Human Genome Sciences negotiate a multi-million-dollar research collaboration agreement.
– 1994: SmithKline Beecham sells its animal health business and purchases Diversified Pharmaceutical Services Inc., a pharmaceutical benefits manager, and Sterling Health, becoming the third-largest over-the-counter medicines company in the world and number one in Europe and the international markets.
– 1995: SmithKline Beecham acquires Sterling Winthrop‘s site in Upper Providence, Pennsylvania.
– 1997: SmithKline Beecham and Incyte Pharmaceuticals create diaDexus, a joint venture to discover and market novel molecular diagnostics based on the use of genomics.